Coffee that has been mixed with Ganoderma lucidum mushrooms (reishi mushrooms) are famous for their medicinal and healthful constituents such as polysaccharides (also called beta-glucans) and proteoglycans, making reishi coffee an amazing treat! To make it, the mushroom powder is ground into a fine consistency before mixing with ground coffee beans; most varieties on the market come either instant or ground versions while there may also be pod versions available for purchase.

Reishi coffee is generally well tolerated, though some individuals may experience side effects. Reishi is known to decrease blood clotting so it should not be combined with medications that affect it and it should also be avoided during pregnancy. Reishi is a potent blood thinner which could interact with antidiabetic medications in some instances.