Ganoderma applanatum is an antitumor and immunomodulatory polypore mushroom with antioxidant, antihyperlipidemic, and hepatoprotective properties. While not edible due to its hard and woody surface, Ganoderma applanatum can still be boiled into tea.

Ganoderma applanatum extracts have shown promising antidiabetic activity in alloxan-induced diabetic rats. Furthermore, these extracts also reduced lipid levels and hepatic enzyme activity within these animals.

Anti-inflammatory

Ganoderma applanatum, or G. applanatum, has long been used as a medicinal mushroom in China (Jong 1992). Although its hard and woody fruiting body cannot be eaten directly, its extract can be made into tea for consumption to provide antiinflammatory, antitumor, and antibacterial benefits; furthermore it may even help treat respiratory conditions like asthma or bronchitis.

Fungi are also rich in essential vitamins and minerals, such as B vitamins, vitamin C and potassium. Germanium, known to possess antitumor and immune-enhancing properties is found within its pores; furthermore it serves as an excellent source of enzymes like superoxide dismutase and lysozyme; its steroid component known as ganodosterone is even said to offer protection from liver diseases.

Researchers have recently demonstrated that Ganoderma applanatum contains terpenes which can prevent cell apoptosis and oxidative stress in mouse liver cells, while also offering protection from benzo(a)pyrene-induced inflammation and oxidative stress in mice. Their authors propose these compounds may prove useful in treating diseases associated with oxidative stress such as liver fibrosis.

One study demonstrated the protective benefits of Ganoderma applanatum polysaccharide extract against carbon tetrachloride (CCl4)-induced interstitial kidney fibrosis in mice by its low levels of proinflammatory cytokines, which helped limit progression by suppressing inflammation reactions that lead to ECM production.

Research article that studied the effects of Ganoderma applanatum extract on cell apoptosis and oxidative damage in human prostate cancer cells showed it significantly improved cell viability while simultaneously decreasing levels of oxidative stress in these cells.

Anti-cancer

Ganoderma applanatum, commonly known as bracket fungus, belongs to the Basidiomycetes family and has long been utilized in traditional medicine for its anticancer properties. Studies have demonstrated its effectiveness at inhibiting cancer cell proliferation and inducing apoptosis while simultaneously having antimicrobial and antifungal activities as well as polysaccharides which possess both antidiabetic and antioxidant effects.

Ganoderma is an effective natural antibiotic, having proven itself effective against several species of bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. Furthermore, Ganoderma’s unique combination of anti-inflammatory, immune-enhancing properties as well as powerful antioxidant properties makes it a powerful solution against oxidative stress.

Ganoderma applanatum mushrooms have also been studied for their anti-tumor effects, with reports of its success against liver cancer, melanoma, leukemia and colon carcinoma, among other cancer types. Ganoderma applanatum contains high amounts of triterpenes – naturally occurring compounds made up of isoprene units found in plants such as triterpenoids – which can be divided into volatile triterpenoids such as sterols or essential oils as well as less volatile diterpenoids or diterpenoids. Ganoderma applanatum also contains C30 pentacyclic triterpenoids called lanostans; these substances contain chemical components including lucidenic acids lucidenic acids alcohol esters lactones or ketones to name just some examples of their capabilities when applied topically against cancerous tumors or other cancerous tumors.

G. applanatum contains compounds which contribute to its anticancer properties, as evidenced by one study showing purified lectins from this mushroom had both cytotoxic and proapoptotic effects against HT-29 colon adenocarcinoma cells. Other research also points out its antiproliferative and immunomodulatory capabilities.

Spores from this mushroom are commonly ground up and used in herbal medicine to treat everything from colds to impotence, with many purporting it as an effective cure. Tea-making with myco-beta-glucans fungus can be done most effectively when steeped for 10 minutes in hot water – this allows it to release its active constituent, myco-beta-glucans which is insoluble in liquid and only becomes bioavailable through exposure to heat for prolonged exposure.

Anti-diabetic

Ganoderma applanatum is a polypore mushroom often found on dead logs or tree wounds, often called Artist’s Conk or Powder-Covered Monkey Fungus or Flesh-Colored Ancient Spirit Plant. This global species can be found growing as long, knobbly conks that can be harvested for medicinal use.

Studies have shown that Ganoderma applanatum contains bioactive polysaccharides with beneficial properties for humans. These polysaccharides include b-1-3 and b-1-6-D-glucans, a-D-mannans, glycoproteins, and heteropolysaccharides that may provide antidiabetic effects and help to manage blood glucose levels.

Ganoderma applanatum also promotes immune health; one study discovered that extracts of Ganoderma applanatum significantly increased red and white blood cell counts in rainbow trout fish as well as hemoglobin, hematocrit, and neutrophil levels in these same fish. Furthermore, Ganoderma may help cardiovascular wellbeing by controlling cholesterol levels.

Ganoderma applanatum is an excellent source of fiber and protein. Additionally, it’s rich in Vitamin C and E as well as germanium which has antimutagenic and immunostimulatory properties.

Ganoderma applanatum can improve cardiovascular health by helping to decrease cholesterol and blood sugar levels by improving the body’s natural ability to process insulin and reduce inflammation. Furthermore, this fungus may prevent atherosclerosis as it lowers triglycerides while simultaneously decreasing blood pressure and blood pressure levels. Hyperlipidemia is linked to coronary heart disease and diabetes mellitus risk factors; by lowering lipids in the bloodstream Ganoderma applanatum helps reduce atherosclerosis risks as well as providing antioxidant and neuroprotective benefits as well as antioxidant and neuroprotective benefits.

Anti-hyperlipidemic

Ganoderma applanatum mushroom has been used since antiquity to treat and prevent various diseases in China, while simultaneously promoting health and longevity. Its medicinal benefits include regulating heart function, relieving asthma and dyspnea symptoms, activating immune system cells and alleviating irregular sleep patterns. Furthermore, detoxification of liver lipids was demonstrated and its antioxidative and hepatoprotective properties further demonstrated when cultured submerged with tea leaves; submersion led to increased activity of fungal metabolites involved in phenolic antioxidative defense such as 2-(4-hydroxyphenyl)ethane-1-ol (tyrosol).

Ganoderma family plants are well known for their polypores, and harvested extensively as medicine in Asia. Furthermore, this genus Ganoderma contains numerous secondary metabolites including volatile triterpenoids and lanostanoids which contain C30 skeleton compounds with diverse pharmacological activities including antimetastatic properties as well as liver protective and antimetastatic activities.

Researchers have recently discovered that Ganoderma polypore has anti-diabetic properties and can effectively prevent adipogenesis in mice, as well as inhibit fat accumulation in abdominal cavities and increase insulin sensitivity among rats. Furthermore, its compounds also increase expressions of apoptosis among adipocytes–an indicator of healthy cells.

Ganoderma polypore has long been recognized for its hepatoprotective effects; now studies suggest it can also act as an effective cancer preventive agent. It inhibits tumor growth by limiting cell migration and metastasis as well as encouraging differentiation of cancerous cells into benign ones. Furthermore, its strong antioxidant properties protect against UV radiation which in turn help protect skin damage caused by sun radiation as well as slow down signs of aging; plus its high concentration of Vitamin D helps maintain bone health!

Anti-hepatoprotective

Ganoderma has been used as a medicinal plant since antiquity, treating many different illnesses while being considered the ultimate adaptogen to promote health and longevity. Ganoderma contains various bioactive compounds and secondary metabolites – polysaccharides, triterpenes, meroterpenoids, phenolic acids, proteins, fatty acids and flavonoids among them – that exhibit antitumor, antihyperlipidemic and hepatoprotective effects as well as immunomodulatory. Some substances identified are identified as terpenoids with strong antimycobacterial activity.

Recent research has demonstrated the power of Ganoderma applanatum extracts as hypolipidemic, antihyperglycemic, hepatoprotective agents. Furthermore, they were found to possess antitumor and antibacterial activity; additionally they are potent antioxidants with immunomodulatory activity as well. A recent alloxan-induced diabetic rats study evaluated these properties of Ganoderma applanatum extracts using both methanol and aqueous Ganoderma applanatum extracts significantly reducing both lipid accumulation in liver and kidney tissues as well as elevations in levels of Hepatic marker enzymes significantly. The results revealed significant reductions of both liver and kidney lipid accumulation as well as elevations in Hepatic marker enzyme levels with use of these methanol/aqueous Ganoderma applanatum extracts having significant reductions seen within diabetic rats using alloxan-induced diabetic rats both extracts having antiidiabetic, hypolipidemic, antihyperglycemic, antihyperglycemic, antihyperglycemic activities while protecting liver from damage by alloxan injection and high levels of Hepatic marker enzyme levels present; this indicates they provide significant relief while hepatic marker enzyme levels elevated due to diabetes as well.

Ganoderma applanatum, also known as Artist’s Conk mushroom, is an abundant white-rot fungus found on living or dead trees that produces long-lived fruiting bodies that can be harvested for tea, tinctures, and other medicinal uses. This species can be found across most continents except Antarctica.

Artist’s Conk mushrooms contain high concentrations of lectins, molecules that bind to certain cells in the body and may help combat cancer. One study demonstrated this ability when purified lectins from Ganoderma applanatum were shown to exert both cytotoxic and proapoptotic effects against HT-29 colon cancer cells as well as antioxidant capacity using DPPH, ABTS+, and hydroxyl radical scavenging assays.