Ganoderma coffee amazon can provide an effective and healthy start to your day, helping increase energy, relax nerves and balance blood pressure. Furthermore, it has also been known to assist digestion, heart health and overall well-being.

Lingzhi (Ganoderma Lucidum) is an edible mushroom known for its polyporous structures and kidney-shaped red color. As an effective nutraceutical with many benefits – including increasing longevity – Lingzhi should not be underestimated!

What is Ganoderma Lucidum?

Ganoderma lucidum, also known as red kidney-shaped polypore mushrooms, belongs to the Ganoderma genus and grows as a basidiomycete fungus that thrives as a parasite on hardwood trees. Ganoderma lucidum stands out among other Ganoderma species by needing wood as part of its substrate for growth, which sets it apart. Furthermore, this species has many medicinal uses. G.lucidum fungus has long been utilized in traditional medicines of various countries including China and Japan, providing many health benefits such as antimicrobial, immunostimulant, cardioprotective effects as well as antihyperglycemic and lipid-lowering effects. B Glucan A is its key bioactive compound and represents one of its major nutraceuticals (defined as foods or parts thereof with pharmaceutical activity beyond basic nutrition; Bach Hi Martins Nascimento Wadt 2018).

Ganoderma, commonly referred to by its Chinese name of Lingzhi, is an Asian medicinal mushroom with wide-reaching therapeutic applications. It’s one of the world’s most frequently consumed herbs due to its anticancer, cardioprotective, and hepatoprotective properties; many believe these bioactives contribute significantly to Ganoderma’s therapeutic effects.

Fungus has long been utilized in traditional medicine practices in both China and Japan for over 2000 years. Its medicinal qualities can be attributed to its polysaccharides which act as anticancer and immunostimulant agents by stimulating T and B lymphocytes, increasing phagocytosis rates, enhancing cytokine production, as well as controlling cancer cell growth and tumor metastasis.

Ganoderma has numerous therapeutic properties, but two that stand out are its antihyperglycemic and hepatoprotective activities. Both in vitro and in vivo studies have demonstrated its antioxidative stress-reduction abilities as well as its improvements on blood sugar levels and lipid metabolism; however, results of clinical trials have varied widely due to different formulations or populations being studied in each. Hence further large controlled clinical trials must be conducted to ascertain G.lucidum’s effect on hyperglycaemia as well as cardiovascular risk factors.

Recent animal research, using a transverse aortic constriction model of pressure overload-induced heart failure in mice, demonstrated that Ganoderma spore oil administration led to normalized ejection fraction, reduced fractional shortening and left ventricular hypertrophy reduction via inhibition of circular RNA Foxo3 expression.

How does Ganoderma Lucidum work?

Ganoderma Lucidum (Reishi mushroom) is a basidiomycete fungus that grows on hardwood trees as a decomposer and produces bioactive molecules with various health benefits. For thousands of years it has been used as traditional Chinese medicine, so this study sought to determine its efficacy against various emerging diseases while simultaneously identifying its bioactive molecules production.

G. lucidum contains various active components, such as polysaccharides and triterpenoids, with several of its active properties being polysaccharides and triterpenoids. Furthermore, its pharmacological activities range from anti-hyperglycemic, hepatoprotective, immunostimulant and antioxidant activities to inhibiting pro-inflammatory cytokines such as IL-1 and TNF- production in LPS-stimulated BV2 microglial cells as well as possessing antimicrobial, antiviral and antifungal activities.

Studies have demonstrated that G. lucidum’s polysaccharide component b glucan has strong scavenging and reducing powers, increasing antioxidant enzyme activity such as superoxide dismutase and catalase activity, while simultaneously suppressing glycolysis and gluconeogenesis-related genes expression levels. A recent strand-specific RNA-seq analysis by Shao et al. demonstrated G. lucidum can resist heat stress by down-regulating key genes involved in glycolysis/gluconeogenesis processes.

Results from this research demonstrate that G. lucidum contains an abundant supply of b glucan, the main polysaccharide found within its core. This material may have significant benefits in treating multiple aspects of disease pathology and could serve as an effective natural therapy solution to address emerging infectious diseases in Africa. So it is imperative that further studies investigate the use of G. lucidum for treating and preventing emerging diseases in Africa, and employ various cultivation methods in order to produce high-quality G. lucidum to achieve desired effects in clinical trials. This research will lay the groundwork for developing novel and effective treatments, and provide new approaches for managing infectious diseases in Africa. Researchers and industry must work collaboratively on this endeavor and create innovative products based on African biodiversity.

What is the best way to take Ganoderma Lucidum?

Ganoderma lucidum, more commonly known as Reishi mushroom, is an antioxidant- and immune-modulating medicinal mushroom used as both dietary supplement or in traditional Chinese medicine practices. Reishi mushrooms have also been touted for potential anti-cancer effects; however there is little scientific proof supporting such claims.

Mushrooms contain multiple polysaccharides and triterpenes that may provide anti-inflammatory, immunomodulatory and antioxidant activities. Furthermore, mushrooms contain many vitamins, minerals, and amino acids – and can be purchased in dried or fresh fruiting bodies, capsules, liquid extracts or tea forms.

Ganoderma Lucidum has been used as a therapeutic agent in traditional Chinese medicine for more than 2000 years to promote general well-being and enhance longevity, as well as for biological/pharmacological activities such as inhibiting cancer cell growth, inducing apoptosis and modulating immunity systems.

Traditional Chinese Medicine makes extensive use of G. lucidum supplements; however, their use has been linked with some severe side effects including liver damage (Bishop et al. Citation 2015). One patient developed fulminant hepatitis after taking Ganopoly(tm) (Encore Health).

Studies on G. lucidum have demonstrated its many pharmacological benefits, from anticancer and cardioprotective to hepatoprotective and immunomodulatory properties. Studies on this herb have also demonstrated an increase in superoxide dismutase activity and catalase production – both essential for protecting cells against reactive oxygen species (ROS), while simultaneously improving cellular function and protecting against stress-related diseases.

Recently, researchers demonstrated that a water-soluble extract of Ganoderma lucidum mycelia protected mice undergoing chemotherapy with anticancer drugs by providing protection to their small intestines from loss of intestinal permeability (Vitak TY, Wasser SP, Nevo E and Sybirna NO.). (

Is Ganoderma Lucidum safe?

Ganoderma lucidum, commonly referred to in traditional Asian medicine as “the mushroom of immortality”, has long been revered for its anticancer, immunomodulatory, and antioxidant properties. It contains polysaccharides, proteins, peptides, sterols, alkaloids, triterpenes, as well as biologically active compounds like alpha-glucosidase inhibitors mannitol organic acids glucosamine and fatty acids which contribute to its therapeutic activity.

Studies have demonstrated the positive impacts of G. lucidum extracts on cardiovascular disease (CVD). This includes being able to lower cholesterol, triglycerides and blood pressure; inhibit oxidation of LDL cholesterol; and prevent clotting abnormalities. Additionally, Ganoderma has also been demonstrated as having various other health benefits, including neuroprotective and antitumor properties.

Ganoderma contains many bioactive constituents that play an essential role in its therapeutic actions, including polysaccharides and triterpenoids. Polysaccharides in particular play an integral part in immunomodulatory, antioxidant, antitumor and antimicrobial activities as well as many others. Ganoderma triterpenoids are responsible for many of its anti-inflammatory and immunoprotective activities. Of particular note are its triterpenoids known as Ganoderic Acids (GAs) – highly oxygenated triterpene-type triterpenoids with unique biological activity. GAs have been shown to exert various effects, such as inhibiting tumor growth and cell proliferation; inducing apoptosis and cell cycle arrest; as well as inhibiting pathways such as NF-kB AP1/uPA, farnesyl protein transferase, and JAK-STAT3.

Ganoderma lucidum is well known for its antioxidant and antitumor properties, but also for its antidiabetic effects. Studies conducted using polysaccharides present in Ganoderma have demonstrated its antidiabetic qualities by decreasing fat tissue mass, decreasing blood sugar levels in rats with high glucose levels, and encouraging insulin secretion.

Ganoderma contains another compound, known as ganodin, which has been shown to possess antibacterial, antifungal and antiparasitic properties. Furthermore, this substance also exhibits immunomodulatory properties including increased production of interleukin-4 and interferon-gamma while simultaneously inhibiting bacteria growth and increasing lymphocyte function – qualities which make this supplement extremely valuable for people suffering from immune deficiencies. Furthermore, ganodin also shows anti-fibrotic and anti-inflammatory qualities as well as helping prevent cardiovascular diseases by lowering blood pressure, lipids levels as well as glucose in diabetic patients.